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Small amounts of acetone are produced in the body by the decarboxylation of ketone bodies.

Certain dietary patterns, including prolonged fasting and high-fat low-carbohydrate dieting, can produce ketosis, in which acetone is formed in body tissue.

Acetone is produced and disposed of in the human body through normal metabolic processes. Pregnant women, nursing mothers and children have higher levels of acetone.

Acetone was first produced by alchemists during the late Middle Ages via the dry distillation of metal acetates (e.g., lead acetate, which produced "spirit of Saturn" (since the alchemical symbol for lead was also the astrological symbol for the planet Saturn)).

It is used as one of the volatile components of some paints and varnishes.

As a heavy-duty degreaser, it is useful in the preparation of metal prior to painting.

It is a colorless, volatile, flammable liquid, and is the simplest ketone.It is a common building block in organic chemistry.Familiar household uses of acetone are as the active ingredient in nail polish remover, and as paint thinner. Reproductive toxicity tests show that it has low potential to cause reproductive problems.Certain health conditions, such as alcoholism and diabetes, can produce ketoacidosis, uncontrollable ketosis that leads to a sharp, and potentially fatal, increase in the acidity of the blood.Since it is a byproduct of fermentation, acetone is a byproduct of the distillery industry.

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